Clinical trials study the safety and effectiveness of interventions and procedures on people’s health. Interventions may include medications, radiation, foods or behaviours, such as exercise. Usually, the treatments in clinical trials are studied in a laboratory and sometimes in animals before they are studied in humans. The goal of clinical trials is to find new and better ways of preventing, diagnosing and treating disease.
AN ANALYSIS OF THE IMPACT OF COLLABORATIVE RESEARCH ON AUSTRALASIAN SURGERY
An analysis of the impact of collaborative research on Australasian Surgery.
A PROSPECTIVE, MULTICENTRE AUDIT OF BCC MARGIN INVOLVEMENT RATE.
A prospective, multicentre audit of BCC margin involvement rate.
A survey of practice in burns thermoregulation
Perioperative hypothermia has been shown to be associated with poor patient outcomes including an increased mortality rate. Patients with major burns are at a particularly high risk of perioperative hypothermia but there is no universally recognised international standard for the monitoring and management of patient body temperature around the time of surgery.
The primary outcome is the consensus concerning the major burn patient body temperature which is deemed to be safe during surgery and in the perioperative period.
An evaluation of WALANT vs non-WALANT surgery in flexor tendon repair.
Flexor tendon injuries most commonly occur following a penetrating injury to the hand or wrist. These are challenging injuries and the standard treatment is surgical repair under general or regional anaesthesia.
‘Wide-awake’ surgery is an emerging technique in hand surgery where a conscious patient is operated on under local anaesthetic. The vasoconstrictive effect of adrenaline (epinephrine) creates a ‘bloodless’ operating field and a tourniquet is not required. The potential advantages include intra-operative testing of the repair; removal of the risks of general anaesthesia; reduced costs; no aerosol generation from intubation therefore reduced risk of COVID-19 spread to healthcare professionals. The aim of this study will be to systematically evaluate the evidence to determine if wide-awake surgery is superior to general/regional anaesthetic in adults who undergo flexor tendon repair.
Chlorhexidine Gluconate versus Povidone-Iodine Skin Antisepsis Prior to Upper Limb Surgery (CIPHUR)
An international, multicentre prospective service evaluation of topical hand antisepsis solution use in hand surgery.
In 2016, the NHS commissioned 196,016 operations for hand conditions, of which 58% were elective. Surgical site infection (SSI) is the most common and costly postoperative complication. Given that 1-35% of hand surgery patients develop SSI and the impending crisis surrounding antimicrobial resistance11, there is a need to reduce SSI following hand surgery.
The World Health Organisation (WHO), United States of America Centre for Disease Control (CDC) and United Kingdom National Institute for Health and Care Excellence (NICE) recommend alcoholic chlorhexidine gluconate (CHG) for preoperative skin preparation to reduce the risk of SSI
To evaluate current upper limb surgery services and SSI rates in the UK, a prospective audit is required.
A study of acral melanoma evaluating aggressive vs conservative surgical management.
A modified Delphi process for research prioritisation in Australasian plastic surgery.
If you would like to know if you are suitable for one of our clinical trials, please use the request form below.